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Course Outline:

Unit 1: Introduction to the Nervous System

L1.1: Basic Organization of CNS & PNS

L1.2: Simple Neural Circuits (VOR, stretch)

L1.3: Electrical Signals in Cells

L1.4: Resting Potential of Neuron Membranes

L1.5: Nernst Equation

Unit 2: Chemical Basis of Electrical Signals

L2.1: TIC and DOC

L2.2: Time & Space in Propagating Signals

L2.3: Ion Channels

L2.4: Post-synaptic Receptors

L2.5: Neurotransmitters and Pathology

Unit 3: Models of Biological Conductors

L3.1: Electrical Variables in Cells

L3.2: Core Conductor Model

L3.3: Observations from Action Potentials

L3.4: Derivation of the Cable Model

L3.5: Time-dependent Solutions

Unit 4: The Hodgkin-Huxley Model

L4.1: Alan Hodgkin and Andrew Huxley

L4.2: Ionic Conductances

L4.3: Derivation of the Hodgkin-Huxley Equation

L4.4: Insights from Hodgkin-Huxley

L4.5: Further insights from Hodgkin-Huxley

Unit 5: Applications of Bioelectricity

L5.2: Epilepsy

L5.3: Drug Addiction

L5.4: Targeted Muscle Reinnervation

L5.5: Optogenetics

Unit 6: Numerical Methods

L6.1: Discrete-Time Solutions to Continuous-Time Problems

L6.2: Euler Method

L6.3: Runge-Kutta Method

L6.4: Solving Hodgkin-Huxley

L6.5: 4th Order Runge-Kutta HH Solution in Python

Unit 7: Practicum

L7.1: Analog Front End

L7.2: Filtering

L7.3: Analog-to-Digital Conversion

L7.4: Full System

L7.5: Bioelectric Prosthesis Control

References

https://nanohub.org/courses/bioelec

https://www.researchgate.net/profile/Pedro_Irazoqui

https://engineering.purdue.edu/Engr/People/NewFaculty/New_Faculty_2005/Irazoqui.htm


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